perl regular expressions substitution/replacement using variables with special characters

Okay I've checked previous similar questions and I've been juggling with different variations of quotemeta but something's still not right. I have a line with a word ID and two words - the first is the wrong word, the second is right. And I'm using a regex to replace the wrong word with the right one. $line = "ANN20021015_0104_XML_16_21 A$xAS A$xASA"; @splits = split("\t",$line); $wrong_word